Vegan Diet Outperforms Mediterranean in Diabetes Risk Reduction, Weight Loss: Study

Friday - 27/06/2025 09:40
A recent study by the Physicians Committee for Responsible Medicine reveals that a low-fat vegan diet significantly reduces dietary acid load compared to the Mediterranean diet. This reduction is associated with weight loss and improved metabolic health. The vegan diet, rich in plant-based foods, promotes an alkaline environment in the body, potentially aiding in weight management and reducing diabetes risk.

A recent study has revealed that a low-fat vegan diet is even more effective than the widely praised Mediterranean diet in reducing the risk of diabetes and promoting weight loss.

Illustration of diabetes

The research, conducted by the Physicians Committee for Responsible Medicine and published in Frontiers in Nutrition, indicates that a vegan diet significantly lowers dietary acid load, a critical factor associated with weight gain and diabetes.

The Power of Plant-Based Eating

The study centered on the impact of a low-fat vegan diet on dietary acid load compared to the Mediterranean diet. Results showed a significant decrease in dietary acid load among participants following the vegan diet, coupled with notable weight loss.

Healthy raw vegan meal

Dr. Hana Kahleova, lead author of the study and director of clinical research at the Physicians Committee, explained, "Consuming acid-producing foods like meat, eggs, and dairy can elevate dietary acid load, leading to inflammation and subsequent weight gain. Replacing these animal products with alkaline plant-based foods such as leafy greens, berries, and legumes can aid weight loss and foster a healthy gut microbiome."

Study Methodology

Researchers conducted a randomized crossover trial involving 62 overweight adults to investigate the link between a vegan diet and diabetes risk reduction. Participants adhered to both a low-fat vegan diet and a Mediterranean diet, each for 16 weeks, separated by a four-week washout period.

Dietary acid load was assessed using Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) scores, with higher scores indicating a greater acid load.

Fresh and colorful vegan ingredients

Key Findings

The study revealed that animal products contribute to increased acid production in the body, leading to a higher dietary acid load and chronic inflammation, potentially disrupting metabolism and promoting weight gain.

Conversely, plant-based diets, being more alkaline, were associated with weight loss, improved insulin sensitivity, and reduced blood pressure.

Both PRAL and NEAP scores significantly decreased in participants on the vegan diet, while no significant change was observed on the Mediterranean diet. This reduction in dietary acid load correlated with weight loss, with participants on the vegan diet experiencing an average weight loss of 13.2 pounds, compared to no change on the Mediterranean diet.

The researchers attribute the weight loss benefits of the vegan diet to its alkalizing effect, which increases the body's pH level, making it less acidic. Foods that contribute to this alkalizing effect include:

  • Vegetables (leafy greens, broccoli, beets, asparagus, garlic, carrots, and cabbage)
  • Fruits (berries, apples, cherries, apricots, and cantaloupe)
  • Legumes (lentils, chickpeas, peas, beans, and soy)
  • Grains (quinoa and millet)

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